Sang-hyun (Song Kang-ho), a respected priest, volunteers for an experimental procedure that may lead to a cure for a deadly virus. He gets infected and dies, but a blood transfusion of unknown origin brings him back to life as a vampire. Now, Sang-hyun is torn between faith and bloodlust, and has a newfound desire for Tae-ju (Kim Ok-vin), the wife of his childhood friend.